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Symbol
Name
ID

Gpx4
glutathione peroxidase 4
MGI:104767

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes	Focal lissencephaly	Pachygyria	Agenesis of corpus callosum	Porencephalic cyst	Cerebellar hypoplasia
Disease(s) Associated with GPX4
spondylometaphyseal dysplasia Sedaghatian type

Mouse Phenotypes		convulsive seizures	abnormal photoreceptor connecting cilium morphology	increased neuron apoptosis	abnormal hippocampus CA3 region morphology	abnormal somatosensory cortex morphology	astrocytosis	abnormal photoreceptor inner segment morphology	abnormal photoreceptor outer segment morphology	disorganized photoreceptor outer segment	neurodegeneration
Availability	Mouse Genotype	convulsive seizures	abnormal photoreceptor connecting cilium morphology	increased neuron apoptosis	abnormal hippocampus CA3 region morphology	abnormal somatosensory cortex morphology	astrocytosis	abnormal photoreceptor inner segment morphology	abnormal photoreceptor outer segment morphology	disorganized photoreceptor outer segment	neurodegeneration
	Gpx4^tm1.1Qra/Gpx4^tm1.1Qra Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺ (conditional)
	Gpx4^tm1Yana/Gpx4^tm1Yana Tg(Crx-cre)1Tfur/0 Tg(Gpx4)#Yana/0 (conditional)
	Gpx4^tm2Marc/Gpx4^tm2Marc Tg(Camk2a-cre)2Gsc/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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